saisimran datta 🧫

MSc Biochemical Engineering at UCL, after Microbiology at Imperial and Prof. Faith Osier's malaria immunology group. I work on how vaccines and biologics are manufactured at scale — process design, scale-up, and the economics of access — most recently from the investment side.

dattasaisimran@gmail.com

Nov 2025 - Jan 2026 Investment Research Intern at Seguro, Dubai — wrote coverage on Eli Lilly, Novo Nordisk and NVIDIA from SEC filings and annual reports, arguing in each case that manufacturing rather than demand was the binding constraint: Wegovy's access shortfall traced to the capacity biologic injectables require, NVIDIA's risk to CoWoS packaging and export licensing.
Oct 2023 - Oct 2025 Analyst (part-time) at G.D Management Consultancy, Dubai — supported GCC launch discussions with MenaPharm and Muscat Pharma on Pharma Bavaria products, covering positioning, demand and distributor fit, and represented the firm at DUPHAT.
Aug 2024 - Oct 2024 Undergraduate Research Assistant in Prof. Faith Osier's malaria immunology group at Imperial College London — purified and characterised merozoite proteins for next-generation malaria vaccine candidates, and traced EXPI293 viability loss in the assay data to a protocol change that cut cell death by 30%.
Jul 2023 - Oct 2023 Logistics & Regulatory Affairs Intern at LIFE Pharma, Dubai — assembled CTD-format registration dossiers to MOHAP and DHA requirements, and wrote the USP-aligned stability summary supporting clopidogrel approval.
Jul 2022 - Sep 2022 Quality Assurance Intern at LIFE Pharma, Dubai — reviewed HPLC chromatograms and batch data for tablet products, flagging out-of-trend results and running root-cause analysis across raw materials, process parameters and analytical factors.

Sep 2025 - Present MSc Biochemical Engineering, University College London — manufacturing strategy, cost-efficiency and scale-up, taught through monoclonal antibody, biofuel and bioprocessing case studies. Averaging 76% across taught modules, on track for a Distinction.
Oct 2022 - Oct 2025 BSc Microbiology, Imperial College London — 2:1, with a First Class final-year dissertation and a First for a second-year tutored dissertation on dynamic Foxp3 expression in autoimmunity. Student mentor on the PASS programme throughout: a root-cause analysis of persistently low lecture attendance led to interventions that raised participation by 80%.

Integrated Bioprocess & Facility Design — ChAdOx1-Vectored Bundibugyo Ebolavirus Vaccine

MSc dissertation, UCL · 2026

Scored six vaccine platforms, from live-attenuated through mRNA and viral-vector, on manufacturability, efficacy, stability, analytical complexity and deployment logistics — concluding that none dominates, and that selection is a trade-off against the outbreak's epidemiological, logistical and regulatory profile. Selected a viral-vector platform on that basis and designed the end-to-end process and facility for one million annual doses: scale-up, equipment design, mass and energy balances, containment and techno-economic evaluation.

Protein Dysregulation in a Triculture Blood–Brain Barrier Model of Chronic Cerebral Malaria

BSc dissertation, Imperial — First Class · 2025

Analysed TEER, permeability, Western blot and ELISA datasets to characterise dysregulation of tight-junction, cytoskeletal, glial and aminopeptidase proteins under chronic infection, then carried the findings through to translation — linking multivalent vaccine design to uptake, access and supply-chain efficiency for malaria vaccines in sub-Saharan Africa.

Hydrohermetic Redesign of Monoclonal Antibody Clarification

MSc, UCL · 2026

Redesigned the clarification train for a mAb process; sizing calculations projected a fourfold reduction in required filtration area, with lower downstream fouling risk.

Bioprocess & engineering — process and facility design, mass and energy balances, equipment sizing, scale-up, containment, techno-economic analysis, GMP.

Laboratory — HPLC, ELISA, Western blot, affinity chromatography, EXPI293 culture and transient transfection, TEER and permeability assays.

Regulatory — CTD-format dossiers, MOHAP and DHA submissions, stability summaries, Certificates of Analysis and Pharmaceutical Product, GMP records.

Data & commercial — R, Python, Excel, statistical analysis; equity and market research, evidence synthesis, executive reporting.

Languages — English, Hindi, Punjabi and Urdu, all fluent.

saisimran datta 🧫

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